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Global gene profiling of aging lungs in Atp8b1 mutant mice
OBJECTIVE: Recent studies implicate cardiolipin oxidation in several age-related diseases. Atp8b1 encoding Type 4 P-type ATPases is a cardiolipin transporter. Mutation in Atp8b1 gene or inflammation of the lungs impairs the capacity of Atp8b1 to clear cardiolipin from lung fluid. However, the link b...
Autores principales: | Soundararajan, Ramani, Stearns, Timothy M., Czachor, Alexander, Fukumoto, Jutaro, Turn, Christina, Westermann-Clark, Emma, Breitzig, Mason, Tan, Lee, Lockey, Richard F., King, Benjamin L., Kolliputi, Narasaiah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076460/ https://www.ncbi.nlm.nih.gov/pubmed/27689529 http://dx.doi.org/10.18632/aging.101056 |
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