The Vesicle Priming Factor CAPS Functions as a Homodimer via C2 Domain Interactions to Promote Regulated Vesicle Exocytosis

Neurotransmitters and peptide hormones are secreted by regulated vesicle exocytosis. CAPS (also known as CADPS) is a 145-kDa cytosolic and peripheral membrane protein required for vesicle docking and priming steps that precede Ca(2+)-triggered vesicle exocytosis. CAPS binds phosphatidylinositol 4,5-...

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Detalles Bibliográficos
Autores principales: Petrie, Matt, Esquibel, Joseph, Kabachinski, Greg, Maciuba, Stephanie, Takahashi, Hirohide, Edwardson, J. Michael, Martin, Thomas F. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076532/
https://www.ncbi.nlm.nih.gov/pubmed/27528604
http://dx.doi.org/10.1074/jbc.M116.728097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076532/
https://www.ncbi.nlm.nih.gov/pubmed/27528604
http://dx.doi.org/10.1074/jbc.M116.728097

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