Cargando…

The Vesicle Priming Factor CAPS Functions as a Homodimer via C2 Domain Interactions to Promote Regulated Vesicle Exocytosis

Neurotransmitters and peptide hormones are secreted by regulated vesicle exocytosis. CAPS (also known as CADPS) is a 145-kDa cytosolic and peripheral membrane protein required for vesicle docking and priming steps that precede Ca(2+)-triggered vesicle exocytosis. CAPS binds phosphatidylinositol 4,5-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Petrie, Matt, Esquibel, Joseph, Kabachinski, Greg, Maciuba, Stephanie, Takahashi, Hirohide, Edwardson, J. Michael, Martin, Thomas F. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076532/ https://www.ncbi.nlm.nih.gov/pubmed/27528604 http://dx.doi.org/10.1074/jbc.M116.728097

Ejemplares similares

Resident CAPS on dense-core vesicles docks and primes vesicles for fusion
por: Kabachinski, Greg, et al.
Publicado: (2016)

CAPS and Munc13 utilize distinct PIP(2)-linked mechanisms to promote vesicle exocytosis
por: Kabachinski, Greg, et al.
Publicado: (2014)

Tomosyn affects dense core vesicle composition but not exocytosis in mammalian neurons
por: Subkhangulova, Aygul, et al.
Publicado: (2023)

Synaptotagmin 1 directs repetitive release by coupling vesicle exocytosis to the Rab3 cycle
por: Cheng, Yunsheng, et al.
Publicado: (2015)

The priming factor CAPS1 regulates dense-core vesicle acidification by interacting with rabconnectin3β/WDR7 in neuroendocrine cells
por: Crummy, Ellen, et al.
Publicado: (2019)

Small molecules that inhibit the late stage of Munc13-4–dependent secretory granule exocytosis in mast cells
por: Bruinsma, Stephen, et al.
Publicado: (2018)

Presynaptic Rac1 controls synaptic strength through the regulation of synaptic vesicle priming
por: Keine, Christian, et al.
Publicado: (2022)

Complexin synchronizes primed vesicle exocytosis and regulates fusion pore dynamics
por: Dhara, Madhurima, et al.
Publicado: (2014)

Interaction between Teneurin-2 and microtubules via EB proteins provides a platform for GABAA receptor exocytosis
por: Ichinose, Sotaro, et al.
Publicado: (2023)

Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors
por: Wang, Dawei, et al.
Publicado: (2021)

Late domain dependent E-cadherin recruitment into extracellular vesicles
por: Bänfer, Sebastian, et al.
Publicado: (2022)

Inhibitors of synaptic vesicle exocytosis reduce surface expression of postsynaptic glutamate receptors
por: Woo, Dong Ho, et al.
Publicado: (2020)

High-speed imaging reveals the bimodal nature of dense core vesicle exocytosis
por: Zhang, Pengcheng, et al.
Publicado: (2022)

COPII vesicles and the expansion of the phagophore
por: Rabouille, Catherine
Publicado: (2019)

Exocytosis—one vesicle at a time
por: Tuma, Rabiya
Publicado: (2003)

Presynaptic morphology and vesicular composition determine vesicle dynamics in mouse central synapses
por: Guillaud, Laurent, et al.
Publicado: (2017)

Individual synaptic vesicles mediate stimulated exocytosis from cochlear inner hair cells
por: Grabner, Chad Paul, et al.
Publicado: (2018)

Recruitment of clathrin to intracellular membranes is sufficient for vesicle formation
por: Küey, Cansu, et al.
Publicado: (2022)

Regulation of the PI3K pathway through a p85α monomer–homodimer equilibrium
por: Cheung, Lydia WT, et al.
Publicado: (2015)

CAPS-1 requires its C2, PH, MHD1 and DCV domains for dense core vesicle exocytosis in mammalian CNS neurons
por: van Keimpema, Linda, et al.
Publicado: (2017)

Synaptic vesicle proteins are selectively delivered to axons in mammalian neurons
por: Watson, Emma T, et al.
Publicado: (2023)

Extracellular Vesicles in Neuroinflammation
por: Marostica, Giulia, et al.
Publicado: (2021)

Synaptobrevin N-terminally bound to syntaxin–SNAP-25 defines the primed vesicle state in regulated exocytosis
por: Walter, Alexander M., et al.
Publicado: (2010)

Intersectin: The Crossroad between Vesicle Exocytosis and Endocytosis
por: Gubar, Olga, et al.
Publicado: (2013)

Sensing Exocytosis and Triggering Endocytosis at Synapses: Synaptic Vesicle Exocytosis–Endocytosis Coupling
por: Lou, Xuelin
Publicado: (2018)

Dimerization of sortilin regulates its trafficking to extracellular vesicles
por: Itoh, Shinsuke, et al.
Publicado: (2018)

Reconstitution of calcium-mediated exocytosis of dense-core vesicles
por: Kreutzberger, Alex J. B., et al.
Publicado: (2017)

Cell volume changes contribute to epithelial morphogenesis in zebrafish Kupffer’s vesicle
por: Dasgupta, Agnik, et al.
Publicado: (2018)

Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis
por: Walter, Alexander M, et al.
Publicado: (2017)

AP2 hemicomplexes contribute independently to synaptic vesicle endocytosis
por: Gu, Mingyu, et al.
Publicado: (2013)

Clathrin modulates vesicle scission, but not invagination shape, in yeast endocytosis
por: Kukulski, Wanda, et al.
Publicado: (2016)

Interferon-γ and Hypoxia Priming Have Limited Effect on the miRNA Landscape of Human Mesenchymal Stromal Cells-Derived Extracellular Vesicles
por: Peltzer, Juliette, et al.
Publicado: (2020)

Curcumin-primed periodontal ligament stem cells-derived extracellular vesicles improve osteogenic ability through the Wnt/β-catenin pathway
por: Lan, Qian, et al.
Publicado: (2023)

Phospholipase Cη2 Activation Redirects Vesicle Trafficking by Regulating F-actin
por: Yamaga, Masaki, et al.
Publicado: (2015)

Transient fusion and selective secretion of vesicle proteins in Phytophthora nicotianae zoospores
por: Zhang, Weiwei, et al.
Publicado: (2013)

Fast retrieval and autonomous regulation of single spontaneously recycling synaptic vesicles
por: Leitz, Jeremy, et al.
Publicado: (2014)

Ciliary Rab28 and the BBSome negatively regulate extracellular vesicle shedding
por: Akella, Jyothi S, et al.
Publicado: (2020)

Vesicle accumulation and exocytosis at sites of plasma membrane disruption
Publicado: (1995)

MicroRNA Exocytosis by Vesicle Fusion in Neuroendocrine Cells
por: Park, Yongsoo
Publicado: (2017)

Biological Features of Extracellular Vesicles and Challenges
por: Zeng, Ye, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_r0ngh4dn7vtllkm8pbdd6pv3ci