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α-Aminoadipic acid protects against retinal disruption through attenuating Müller cell gliosis in a rat model of acute ocular hypertension

OBJECTIVE: Ocular hypertension is an important risk factor for glaucoma. The purpose of this study was to investigate the gliotoxic effects of α-aminoadipic acid (AAA) in a rat model of AOH and its underlying mechanisms. MATERIALS AND METHODS: In the rat model of acute ocular hypertension (AOH), int...

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Detalles Bibliográficos
Autores principales: Wang, Xiaolei, Su, Jier, Ding, Jingwen, Han, Song, Ma, Wei, Luo, Hong, Hughes, Guy, Meng, Zhaoyang, Yin, Yi, Wang, Yanling, Li, Junfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076852/
https://www.ncbi.nlm.nih.gov/pubmed/27799744
http://dx.doi.org/10.2147/DDDT.S105362