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A Combination of Diffusion and Active Translocation Localizes Myosin 10 to the Filopodial Tip

Myosin 10 is an actin-based molecular motor that localizes to the tips of filopodia in mammalian cells. To understand how it is targeted to this distinct region of the cell, we have used total internal reflection fluorescence microscopy to study the movement of individual full-length and truncated G...

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Detalles Bibliográficos
Autores principales: Baboolal, Thomas G., Mashanov, Gregory I., Nenasheva, Tatiana A., Peckham, Michelle, Molloy, Justin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077179/
https://www.ncbi.nlm.nih.gov/pubmed/27566544
http://dx.doi.org/10.1074/jbc.M116.730689