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Long Non-Coding RNA (lncRNA) Urothelial Carcinoma-Associated 1 (UCA1) Enhances Tamoxifen Resistance in Breast Cancer Cells via Inhibiting mTOR Signaling Pathway

BACKGROUND: Long non-coding RNA (lncRNA) UCA1 is an oncogene in breast cancer. The purpose of this study was to investigate the role of UCA1 in tamoxifen resistance of estrogen receptor positive breast cancer cells. MATERIAL/METHODS: Tamoxifen sensitive MCF-7 cells were transfected for UCA1 overexpr...

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Detalles Bibliográficos
Autores principales: Wu, Chihua, Luo, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077288/
https://www.ncbi.nlm.nih.gov/pubmed/27765938
http://dx.doi.org/10.12659/MSM.900689