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Change in Off-Label Use of Bone Morphogenetic Protein in Spine Surgery and Associations with Adverse Outcome
Study Design Retrospective cohort study. Objective The U.S. Food and Drug Administration issued a warning in 2008 against off-label bone morphogenetic protein (BMP-2) use. We aimed to determine (off-label) BMP-2 use in two periods and associations with complications. Methods We included 340,393 pati...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Georg Thieme Verlag KG
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077709/ https://www.ncbi.nlm.nih.gov/pubmed/27781184 http://dx.doi.org/10.1055/s-0036-1571284 |