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MDM2 and P53 polymorphisms contribute together to the risk and survival of prostate cancer

The p53 gene and MDM2 gene play critical roles in cell cycle arrest and apoptosis together. Here, we evaluated the associations of prostate cancer risk and survival with the joint effects of mdm2 and p53 polymorphisms. Totally 1,193 cases and 1,310 age frequency-matched controls were included in the...

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Detalles Bibliográficos
Autores principales: Xue, Li, Han, Xiujuan, Liu, Rongrong, Wang, Ziming, Li, Hecheng, Chen, Qi, Zhang, Peng, Wang, Zhenlong, Chong, Tie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077979/
https://www.ncbi.nlm.nih.gov/pubmed/26025918
http://dx.doi.org/10.18632/oncotarget.3923