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Inhibition of c-FLIP(L) expression by miRNA-708 increases the sensitivity of renal cancer cells to anti-cancer drugs

Dysregulation of the anti-apoptotic protein, cellular FLICE-like inhibitory protein (c-FLIP), has been associated with tumorigenesis and chemoresistance in various human cancers. Therefore, c-FLIP is an excellent target for therapeutic intervention. MicroRNAs (miRNAs) are small non-coding RNAs that...

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Detalles Bibliográficos
Autores principales: Kim, Eun-Ae, Kim, Sang-Woo, Nam, Jehyun, Sung, Eon-Gi, Song, In-Hwan, Kim, Joo-Young, Kwon, Taeg Kyu, Lee, Tae-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077980/
https://www.ncbi.nlm.nih.gov/pubmed/27092874
http://dx.doi.org/10.18632/oncotarget.7149