Cancer-selective cytotoxic Ca(2+) overload in acute myeloid leukemia cells and attenuation of disease progression in mice by synergistically acting polyphenols curcumin and carnosic acid

Acute myeloid leukemia (AML) is an aggressive hematologic malignancy characterized by extremely heterogeneous molecular and biologic abnormalities that hamper the development of effective targeted treatment modalities. While AML cells are highly sensitive to cytotoxic Ca(2+) overload, the feasibilit...

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Detalles Bibliográficos
Autores principales: Pesakhov, Stella, Nachliely, Matan, Barvish, Zeev, Aqaqe, Nasma, Schwartzman, Bar, Voronov, Elena, Sharoni, Yoav, Studzinski, George P., Fishman, Daniel, Danilenko, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077981/
https://www.ncbi.nlm.nih.gov/pubmed/26870993
http://dx.doi.org/10.18632/oncotarget.7240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077981/
https://www.ncbi.nlm.nih.gov/pubmed/26870993
http://dx.doi.org/10.18632/oncotarget.7240

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