Cell line with endogenous EGFR(vIII) expression is a suitable model for research and drug development purposes

Glioblastoma is the most common and malignant brain tumor, characterized by high cellular heterogeneity. About 50% of glioblastomas are positive for EGFR amplification, half of which express accompanying EGFR mutation, encoding truncated and constitutively active receptor termed EGFR(vIII). Currentl...

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Detalles Bibliográficos
Autores principales: Stec, Wojciech J., Rosiak, Kamila, Siejka, Paulina, Peciak, Joanna, Popeda, Marta, Banaszczyk, Mateusz, Pawlowska, Roza, Treda, Cezary, Hulas-Bigoszewska, Krystyna, Piaskowski, Sylwester, Stoczynska-Fidelus, Ewelina, Rieske, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077985/
https://www.ncbi.nlm.nih.gov/pubmed/27004406
http://dx.doi.org/10.18632/oncotarget.8201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077985/
https://www.ncbi.nlm.nih.gov/pubmed/27004406
http://dx.doi.org/10.18632/oncotarget.8201

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