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The DNA resection protein CtIP promotes mammary tumorigenesis

Many DNA repair factors act to suppress tumor formation by preserving genomic stability. Similarly, the CtIP protein, which interacts with the BRCA1 tumor suppressor, is also thought to have tumor suppression activity. Through its role in DNA end resection, CtIP facilitates DNA double-strand break (...

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Detalles Bibliográficos
Autores principales: Reczek, Colleen R., Shakya, Reena, Miteva, Yana, Szabolcs, Matthias, Ludwig, Thomas, Baer, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078005/
https://www.ncbi.nlm.nih.gov/pubmed/27058754
http://dx.doi.org/10.18632/oncotarget.8605