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The DNA resection protein CtIP promotes mammary tumorigenesis
Many DNA repair factors act to suppress tumor formation by preserving genomic stability. Similarly, the CtIP protein, which interacts with the BRCA1 tumor suppressor, is also thought to have tumor suppression activity. Through its role in DNA end resection, CtIP facilitates DNA double-strand break (...
Autores principales: | Reczek, Colleen R., Shakya, Reena, Miteva, Yana, Szabolcs, Matthias, Ludwig, Thomas, Baer, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078005/ https://www.ncbi.nlm.nih.gov/pubmed/27058754 http://dx.doi.org/10.18632/oncotarget.8605 |
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