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The oleocanthal-based homovanillyl sinapate as a novel c-Met inhibitor

The hepatocyte growth factor (HGF)/mesenchymal-epithelial transition factor (c-Met) signaling axis has gained considerable attention as an attractive molecular target for therapeutic blockade of cancer. Inspired by the chemical structure of S (−)-oleocanthal, a natural secoiridoid from extra-virgin...

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Detalles Bibliográficos
Autores principales: Mohyeldin, Mohamed M., Akl, Mohamed R., Ebrahim, Hassan Y., Dragoi, Ana Maria, Dykes, Samantha, Cardelli, James A., El Sayed, Khalid A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078011/
https://www.ncbi.nlm.nih.gov/pubmed/27086914
http://dx.doi.org/10.18632/oncotarget.8681