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DNA polymerase iota (Pol ι) promotes invasion and metastasis of esophageal squamous cell carcinoma
DNA polymerase iota (Pol ι) is an error-prone DNA polymerase involved in translesion DNA synthesis (TLS) that contributes to the accumulation of DNA mutations. We recently showed that Pol ι is overexpressed in human esophageal squamous cell cancer (ESCC) tissues which promotes ESCC' progression...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078012/ https://www.ncbi.nlm.nih.gov/pubmed/27057634 http://dx.doi.org/10.18632/oncotarget.8580 |