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A KSHV microRNA enhances viral latency and induces angiogenesis by targeting GRK2 to activate the CXCR2/AKT pathway

Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi's sarcoma (KS), primary effusion lymphoma (PEL) and multicentric Castleman's disease (MCD). Most tumor cells in these malignancies are latently infected by KSHV. Thus, viral latency is critical for the dev...

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Detalles Bibliográficos
Autores principales: Li, Wan, Jia, Xuemei, Shen, Chenyou, Zhang, Mi, Xu, Jingyun, Shang, Yuancui, Zhu, Kaixiang, Hu, Minmin, Yan, Qin, Qin, Di, Lee, Myung-Shin, Zhu, Jianzhong, Lu, Hongmei, Krueger, Brian J., Renne, Rolf, Gao, Shou-Jiang, Lu, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078013/
https://www.ncbi.nlm.nih.gov/pubmed/27058419
http://dx.doi.org/10.18632/oncotarget.8591