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BLM promotes the activation of Fanconi Anemia signaling pathway

Mutations in the human RecQ helicase, BLM, causes Bloom Syndrome, which is a rare autosomal recessive disorder and characterized by genomic instability and an increased risk of cancer. Fanconi Anemia (FA), resulting from mutations in any of the 19 known FA genes and those yet to be known, is also ch...

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Detalles Bibliográficos
Autores principales: Panneerselvam, Jayabal, Wang, Hong, Zhang, Jun, Che, Raymond, Yu, Herbert, Fei, Peiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078018/
https://www.ncbi.nlm.nih.gov/pubmed/27083049
http://dx.doi.org/10.18632/oncotarget.8707