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UBE2D3 gene overexpression increases radiosensitivity of EC109 esophageal cancer cells in vitro and in vivo

Ubiquitin-conjugating enzyme E2D3 (UBE2D3), a key component in ubiquitin (Ub) proteasome system, plays a crucial role in tumorigenesis. We previously found that it is bound to hTERT, and UBE2D3 could attenuate radiosensitivity of human breast cancer cells. Here we investigated a contributing role of...

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Detalles Bibliográficos
Autores principales: Gao, Xiaojia, Wang, Wenbo, Yang, Hui, Wu, Lin, He, Zhongshi, Zhou, Shuliang, Zhao, Hong, Fu, Zhenming, Zhou, Fuxiang, Zhou, Yunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078032/
https://www.ncbi.nlm.nih.gov/pubmed/27105523
http://dx.doi.org/10.18632/oncotarget.8869