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Palmitoylation regulates the intracellular trafficking and stability of c-Met

c-Met is a receptor tyrosine kinase whose activity can promote both mitogenic and motogenic phenotypes involved in tissue development and cancer progression. Herein, we report the first evidence that c-Met is palmitoylated and that palmitoylation facilitates its trafficking and stability. Inhibition...

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Detalles Bibliográficos
Autores principales: Coleman, David T., Gray, Alana L., Kridel, Steven J., Cardelli, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078042/
https://www.ncbi.nlm.nih.gov/pubmed/27081699
http://dx.doi.org/10.18632/oncotarget.8706