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Palmitoylation regulates the intracellular trafficking and stability of c-Met
c-Met is a receptor tyrosine kinase whose activity can promote both mitogenic and motogenic phenotypes involved in tissue development and cancer progression. Herein, we report the first evidence that c-Met is palmitoylated and that palmitoylation facilitates its trafficking and stability. Inhibition...
Autores principales: | Coleman, David T., Gray, Alana L., Kridel, Steven J., Cardelli, James A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078042/ https://www.ncbi.nlm.nih.gov/pubmed/27081699 http://dx.doi.org/10.18632/oncotarget.8706 |
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