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QKI5-mediated alternative splicing of the histone variant macroH2A1 regulates gastric carcinogenesis
Alternative pre-mRNA splicing is a key mechanism for increasing proteomic diversity and modulating gene expression. Emerging evidence indicated that the splicing program is frequently dysregulated during tumorigenesis. Cancer cells produce protein isoforms that can promote growth and survival. The R...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078054/ https://www.ncbi.nlm.nih.gov/pubmed/27092877 http://dx.doi.org/10.18632/oncotarget.8739 |