A novel TP53 variant (rs78378222 A > C) in the polyadenylation signal is associated with increased cancer susceptibility: evidence from a meta-analysis

Polymorphisms in TP53 are involved in the progression of different types of cancer. A rare novel TP53 variant (rs78378222 A > C allele) was found via whole-genome sequencing in 2011. This variant was shown to significantly increase the risk of glioma, colorectal adenoma and prostate cancer. Funct...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Wu, Xue-Song, He, Jing, Ma, Tianjiao, Lei, Wei, Shen, Zhen-Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078057/
https://www.ncbi.nlm.nih.gov/pubmed/27147571
http://dx.doi.org/10.18632/oncotarget.9056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078057/
https://www.ncbi.nlm.nih.gov/pubmed/27147571
http://dx.doi.org/10.18632/oncotarget.9056

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