Cisplatin selects for stem-like cells in osteosarcoma by activating Notch signaling

Notch signaling regulates normal stem cells and is also thought to regulate cancer stem cells (CSCs). Recent data indicate that Notch signaling plays a role in the development and progression of osteosarcoma, however the regulation of Notch in chemo-resistant stem-like cells has not yet been fully e...

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Detalles Bibliográficos
Autores principales: Yu, Ling, Fan, Zhengfu, Fang, Shuo, Yang, Jian, Gao, Tian, Simões, Bruno M., Eyre, Rachel, Guo, Weichun, Clarke, Robert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078075/
https://www.ncbi.nlm.nih.gov/pubmed/27102300
http://dx.doi.org/10.18632/oncotarget.8849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078075/
https://www.ncbi.nlm.nih.gov/pubmed/27102300
http://dx.doi.org/10.18632/oncotarget.8849

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