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Cisplatin selects for stem-like cells in osteosarcoma by activating Notch signaling
Notch signaling regulates normal stem cells and is also thought to regulate cancer stem cells (CSCs). Recent data indicate that Notch signaling plays a role in the development and progression of osteosarcoma, however the regulation of Notch in chemo-resistant stem-like cells has not yet been fully e...
Autores principales: | Yu, Ling, Fan, Zhengfu, Fang, Shuo, Yang, Jian, Gao, Tian, Simões, Bruno M., Eyre, Rachel, Guo, Weichun, Clarke, Robert B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078075/ https://www.ncbi.nlm.nih.gov/pubmed/27102300 http://dx.doi.org/10.18632/oncotarget.8849 |
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