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NLRX1 suppresses tumorigenesis and attenuates histiocytic sarcoma through the negative regulation of NF-λB signaling

Histiocytic sarcoma is an uncommon malignancy in both humans and veterinary species. Research exploring the pathogenesis of this disease is scarce; thus, diagnostic and therapeutic options for patients are limited. Recent publications have suggested a role for the NLR, NLRX1, in acting as a tumor su...

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Detalles Bibliográficos
Autores principales: Coutermarsh-Ott, Sheryl, Simmons, Alysha, Capria, Vittoria, LeRoith, Tanya, Wilson, Justin E., Heid, Bettina, Philipson, Casandra W., Qin, Qizhi, Hontecillas-Magarzo, Raquel, Bassaganya-Riera, Josep, Ting, Jenny P-Y, Dervisis, Nikolaos, Allen, Irving C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078078/
https://www.ncbi.nlm.nih.gov/pubmed/27105514
http://dx.doi.org/10.18632/oncotarget.8861