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Spheroid cancer stem cells display reprogrammed metabolism and obtain energy by actively running the tricarboxylic acid (TCA) cycle

The Warburg effect is a metabolic hallmark of cancer cells; cancer cells, unlike normal cells, exclusively activate glycolysis, even in the presence of enough oxygen. On the other hand, intratumoral heterogeneity is currently of interest in cancer research, including that involving cancer stem cells...

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Detalles Bibliográficos
Autores principales: Sato, Masakazu, Kawana, Kei, Adachi, Katsuyuki, Fujimoto, Asaha, Yoshida, Mitsuyo, Nakamura, Hiroe, Nishida, Haruka, Inoue, Tomoko, Taguchi, Ayumi, Takahashi, Juri, Eguchi, Satoko, Yamashita, Aki, Tomio, Kensuke, Wada-Hiraike, Osamu, Oda, Katsutoshi, Nagamatsu, Takeshi, Osuga, Yutaka, Fujii, Tomoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078095/
https://www.ncbi.nlm.nih.gov/pubmed/27120812
http://dx.doi.org/10.18632/oncotarget.8947