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Spheroid cancer stem cells display reprogrammed metabolism and obtain energy by actively running the tricarboxylic acid (TCA) cycle
The Warburg effect is a metabolic hallmark of cancer cells; cancer cells, unlike normal cells, exclusively activate glycolysis, even in the presence of enough oxygen. On the other hand, intratumoral heterogeneity is currently of interest in cancer research, including that involving cancer stem cells...
Autores principales: | Sato, Masakazu, Kawana, Kei, Adachi, Katsuyuki, Fujimoto, Asaha, Yoshida, Mitsuyo, Nakamura, Hiroe, Nishida, Haruka, Inoue, Tomoko, Taguchi, Ayumi, Takahashi, Juri, Eguchi, Satoko, Yamashita, Aki, Tomio, Kensuke, Wada-Hiraike, Osamu, Oda, Katsutoshi, Nagamatsu, Takeshi, Osuga, Yutaka, Fujii, Tomoyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078095/ https://www.ncbi.nlm.nih.gov/pubmed/27120812 http://dx.doi.org/10.18632/oncotarget.8947 |
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