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Oncogenic ALK regulates EMT in non-small cell lung carcinoma through repression of the epithelial splicing regulatory protein 1

A subset of Non-Small Cell Lung Carcinoma (NSCLC) carries chromosomal rearrangements involving the Anaplastic Lymphoma Kinase (ALK) gene. ALK-rearranged NSCLC are typically adenocarcinoma characterized by a solid signet-ring cell pattern that is frequently associated with a metastatic phenotype. Rec...

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Detalles Bibliográficos
Autores principales: Voena, Claudia, Varesio, Lydia M., Zhang, Liye, Menotti, Matteo, Poggio, Teresa, Panizza, Elena, Wang, Qi, Minero, Valerio G., Fagoonee, Sharmila, Compagno, Mara, Altruda, Fiorella, Monti, Stefano, Chiarle, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078097/
https://www.ncbi.nlm.nih.gov/pubmed/27119231
http://dx.doi.org/10.18632/oncotarget.8955