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Brain tumor modeling using the CRISPR/Cas9 system: state of the art and view to the future

Although brain tumors have been known tremendously over the past decade, there are still many problems to be solved. The etiology of brain tumors is not well understood and the treatment remains modest. There is in great need to develop a suitable brain tumor models that faithfully mirror the etiolo...

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Detalles Bibliográficos
Autores principales: Mao, Xiao-Yuan, Dai, Jin-Xiang, Zhou, Hong-Hao, Liu, Zhao-Qian, Jin, Wei-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078110/
https://www.ncbi.nlm.nih.gov/pubmed/26993776
http://dx.doi.org/10.18632/oncotarget.8075