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DNA Damage: From Chronic Inflammation to Age-Related Deterioration

To lessen the “wear and tear” of existence, cells have evolved mechanisms that continuously sense DNA lesions, repair DNA damage and restore the compromised genome back to its native form. Besides genome maintenance pathways, multicellular organisms may also employ adaptive and innate immune mechani...

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Detalles Bibliográficos
Autores principales: Ioannidou, Anna, Goulielmaki, Evi, Garinis, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078321/
https://www.ncbi.nlm.nih.gov/pubmed/27826317
http://dx.doi.org/10.3389/fgene.2016.00187