Multiple Cranial Organ Defects after Conditionally Knocking Out Fgf10 in the Neural Crest

Fgf10 is necessary for the development of a number of organs that fail to develop or are reduced in size in the null mutant. Here we have knocked out Fgf10 specifically in the neural crest driven by Wnt1cre. The Wnt1creFgf10fl/fl mouse phenocopies many of the null mutant defects, including cleft pal...

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Detalles Bibliográficos
Autores principales: Teshima, Tathyane H. N., Lourenco, Silvia V., Tucker, Abigail S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078472/
https://www.ncbi.nlm.nih.gov/pubmed/27826253
http://dx.doi.org/10.3389/fphys.2016.00488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078472/
https://www.ncbi.nlm.nih.gov/pubmed/27826253
http://dx.doi.org/10.3389/fphys.2016.00488

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