Genetic Factors of the Disease Course After Sepsis: Rare Deleterious Variants Are Predictive

Sepsis is a life-threatening organ dysfunction caused by dysregulated host response to infection. For its clinical course, host genetic factors are important and rare genomic variants are suspected to contribute. We sequenced the exomes of 59 Greek and 15 German patients with bacterial sepsis divide...

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Detalles Bibliográficos
Autores principales: Taudien, Stefan, Lausser, Ludwig, Giamarellos-Bourboulis, Evangelos J., Sponholz, Christoph, Schöneweck, Franziska, Felder, Marius, Schirra, Lyn-Rouven, Schmid, Florian, Gogos, Charalambos, Groth, Susann, Petersen, Britt-Sabina, Franke, Andre, Lieb, Wolfgang, Huse, Klaus, Zipfel, Peter F., Kurzai, Oliver, Moepps, Barbara, Gierschik, Peter, Bauer, Michael, Scherag, André, Kestler, Hans A., Platzer, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078585/
https://www.ncbi.nlm.nih.gov/pubmed/27639823
http://dx.doi.org/10.1016/j.ebiom.2016.08.037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078585/
https://www.ncbi.nlm.nih.gov/pubmed/27639823
http://dx.doi.org/10.1016/j.ebiom.2016.08.037

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