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Genetic Factors of the Disease Course after Sepsis: A Genome-Wide Study for 28 Day Mortality

Sepsis is the dysregulated host response to an infection which leads to life-threatening organ dysfunction that varies by host genomic factors. We conducted a genome-wide association study (GWAS) in 740 adult septic patients and focused on 28 day mortality as outcome. Variants with suggestive eviden...

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Detalles Bibliográficos
Autores principales: Scherag, André, Schöneweck, Franziska, Kesselmeier, Miriam, Taudien, Stefan, Platzer, Matthias, Felder, Marius, Sponholz, Christoph, Rautanen, Anna, Hill, Adrian V.S., Hinds, Charles J., Hossain, Hamid, Suttorp, Norbert, Kurzai, Oliver, Slevogt, Hortense, Giamarellos-Bourboulis, Evangelos J., Armaganidis, Apostolos, Trips, Evelyn, Scholz, Markus, Brunkhorst, Frank M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078589/
https://www.ncbi.nlm.nih.gov/pubmed/27639821
http://dx.doi.org/10.1016/j.ebiom.2016.08.043