Effects of a novel β–lapachone derivative on Trypanosoma cruzi: Parasite death involving apoptosis, autophagy and necrosis

Natural products comprise valuable sources for new antiparasitic drugs. Here we tested the effects of a novel β–lapachone derivative on Trypanosoma cruzi parasite survival and proliferation and used microscopy and cytometry techniques to approach the mechanism(s) underlying parasite death. The selec...

Descripción completa

Detalles Bibliográficos
Autores principales: dos Anjos, Danielle Oliveira, Sobral Alves, Eliomara Sousa, Gonçalves, Vinicius Tomaz, Fontes, Sheila Suarez, Nogueira, Mateus Lima, Suarez-Fontes, Ana Márcia, Neves da Costa, João Batista, Rios-Santos, Fabricio, Vannier-Santos, Marcos André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078628/
https://www.ncbi.nlm.nih.gov/pubmed/27770751
http://dx.doi.org/10.1016/j.ijpddr.2016.10.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078628/
https://www.ncbi.nlm.nih.gov/pubmed/27770751
http://dx.doi.org/10.1016/j.ijpddr.2016.10.003

Ejemplares similares