Effects of a novel β–lapachone derivative on Trypanosoma cruzi: Parasite death involving apoptosis, autophagy and necrosis

Natural products comprise valuable sources for new antiparasitic drugs. Here we tested the effects of a novel β–lapachone derivative on Trypanosoma cruzi parasite survival and proliferation and used microscopy and cytometry techniques to approach the mechanism(s) underlying parasite death. The selec...

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Detalles Bibliográficos
Autores principales: dos Anjos, Danielle Oliveira, Sobral Alves, Eliomara Sousa, Gonçalves, Vinicius Tomaz, Fontes, Sheila Suarez, Nogueira, Mateus Lima, Suarez-Fontes, Ana Márcia, Neves da Costa, João Batista, Rios-Santos, Fabricio, Vannier-Santos, Marcos André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078628/
https://www.ncbi.nlm.nih.gov/pubmed/27770751
http://dx.doi.org/10.1016/j.ijpddr.2016.10.003

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