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Red blood cell thickness is evolutionarily constrained by slow, hemoglobin-restricted diffusion in cytoplasm
During capillary transit, red blood cells (RBCs) must exchange large quantities of CO(2) and O(2) in typically less than one second, but the degree to which this is rate-limited by diffusion through cytoplasm is not known. Gas diffusivity is intuitively assumed to be fast and this would imply that t...
Autores principales: | Richardson, Sarah L., Swietach, Pawel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078773/ https://www.ncbi.nlm.nih.gov/pubmed/27777410 http://dx.doi.org/10.1038/srep36018 |
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