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Disabled-2 Determines Commitment of a Pre-adipocyte Population in Juvenile Mice

Disabled-2 (Dab2) is a widely expressed clathrin binding endocytic adaptor protein and known for the endocytosis of the low-density lipoprotein (LDL) family receptors. Dab2 also modulates endosomal Ras/MAPK (Erk1/2) activity by regulating the disassembly of Grb2/Sos1 complexes associated with clathr...

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Detalles Bibliográficos
Autores principales: Tao, Wensi, Moore, Robert, Meng, Yue, Yeasky, Toni M., Smith, Elizabeth R., Xu, Xiang-Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078790/
https://www.ncbi.nlm.nih.gov/pubmed/27779214
http://dx.doi.org/10.1038/srep35947