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Origins of chromosomal rearrangement hotspots in the human genome: evidence from the AZFa deletion hotspots

BACKGROUND: The origins of the recombination hotspots that are a common feature of both allelic and non-allelic homologous recombination in the human genome are poorly understood. We have investigated, by comparative sequencing, the evolution of two hotspots of non-allelic homologous recombination o...

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Detalles Bibliográficos
Autores principales: Hurles, Matthew E, Willey, David, Matthews, Lucy, Hussain, Syed Sufyan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC507880/
https://www.ncbi.nlm.nih.gov/pubmed/15287977
http://dx.doi.org/10.1186/gb-2004-5-8-r55