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Simvastatin induces cell cycle arrest and inhibits proliferation of bladder cancer cells via PPARγ signalling pathway

Simvastatin is currently one of the most common drugs for old patients with hyperlipidemia, hypercholesterolemia and atherosclerotic diseases by reducing cholesterol level and anti-lipid properties. Importantly, simvastatin has also been reported to have anti-tumor effect, but the underlying mechani...

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Detalles Bibliográficos
Autores principales: Wang, Gang, Cao, Rui, Wang, Yongzhi, Qian, Guofeng, Dan, Han C., Jiang, Wei, Ju, Lingao, Wu, Min, Xiao, Yu, Wang, Xinghuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078845/
https://www.ncbi.nlm.nih.gov/pubmed/27779188
http://dx.doi.org/10.1038/srep35783