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Simvastatin induces cell cycle arrest and inhibits proliferation of bladder cancer cells via PPARγ signalling pathway
Simvastatin is currently one of the most common drugs for old patients with hyperlipidemia, hypercholesterolemia and atherosclerotic diseases by reducing cholesterol level and anti-lipid properties. Importantly, simvastatin has also been reported to have anti-tumor effect, but the underlying mechani...
Autores principales: | Wang, Gang, Cao, Rui, Wang, Yongzhi, Qian, Guofeng, Dan, Han C., Jiang, Wei, Ju, Lingao, Wu, Min, Xiao, Yu, Wang, Xinghuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078845/ https://www.ncbi.nlm.nih.gov/pubmed/27779188 http://dx.doi.org/10.1038/srep35783 |
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