Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia

Causes of the well-documented association between low levels of cognitive functioning and many adverse neuropsychiatric outcomes, poorer physical health and earlier death remain unknown. We used linkage disequilibrium regression and polygenic profile scoring to test for shared genetic aetiology betw...

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Detalles Bibliográficos
Autores principales: Hagenaars, S P, Harris, S E, Davies, G, Hill, W D, Liewald, D C M, Ritchie, S J, Marioni, R E, Fawns-Ritchie, C, Cullen, B, Malik, R, Worrall, B B, Sudlow, C L M, Wardlaw, J M, Gallacher, J, Pell, J, McIntosh, A M, Smith, D J, Gale, C R, Deary, I J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078856/
https://www.ncbi.nlm.nih.gov/pubmed/26809841
http://dx.doi.org/10.1038/mp.2015.225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078856/
https://www.ncbi.nlm.nih.gov/pubmed/26809841
http://dx.doi.org/10.1038/mp.2015.225

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