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Brain iron accumulation affects myelin-related molecular systems implicated in a rare neurogenetic disease family with neuropsychiatric features
The ‘neurodegeneration with brain iron accumulation' (NBIA) disease family entails movement or cognitive impairment, often with psychiatric features. To understand how iron loading affects the brain, we studied mice with disruption of two iron regulatory genes, hemochromatosis (Hfe) and transfe...
Autores principales: | Heidari, M, Johnstone, D M, Bassett, B, Graham, R M, Chua, A C G, House, M J, Collingwood, J F, Bettencourt, C, Houlden, H, Ryten, M, Olynyk, J K, Trinder, D, Milward, E A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078858/ https://www.ncbi.nlm.nih.gov/pubmed/26728570 http://dx.doi.org/10.1038/mp.2015.192 |
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