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Alkaloids from piper longum protect dopaminergic neurons against inflammation-mediated damage induced by intranigral injection of lipopolysaccharide

BACKGROUND: Alkaloids from Piper longum (PLA), extracted from P. longum, have potent anti-inflammatory effects. The aim of this study was to investigate whether PLA could protect dopaminergic neurons against inflammation-mediated damage by inhibiting microglial activation using a lipopolysaccharide...

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Detalles Bibliográficos
Autores principales: He, Huan, Guo, Wei-Wei, Xu, Rong-Rong, Chen, Xiao-Qing, Zhang, Nan, Wu, Xia, Wang, Xiao-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078945/
https://www.ncbi.nlm.nih.gov/pubmed/27776556
http://dx.doi.org/10.1186/s12906-016-1392-6