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Fast type I interferon response protects astrocytes from flavivirus infection and virus-induced cytopathic effects

BACKGROUND: Neurotropic flaviviruses such as tick-borne encephalitis virus (TBEV), Japanese encephalitis virus (JEV), West Nile virus (WNV), and Zika virus (ZIKV) are causative agents of severe brain-related diseases including meningitis, encephalitis, and microcephaly. We have previously shown that...

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Detalles Bibliográficos
Autores principales: Lindqvist, Richard, Mundt, Filip, Gilthorpe, Jonathan D., Wölfel, Silke, Gekara, Nelson O., Kröger, Andrea, Överby, Anna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078952/
https://www.ncbi.nlm.nih.gov/pubmed/27776548
http://dx.doi.org/10.1186/s12974-016-0748-7