Cargando…
S100A8/A9, a potent serum and molecular imaging biomarker for synovial inflammation and joint destruction in seronegative experimental arthritis
BACKGROUND: Seronegative joint diseases are characterized by a lack of well-defined biomarkers since autoantibodies are not elevated. Calprotectin (S100A8/A9) is a damage-associated molecular pattern (DAMP) which is released by activated phagocytes, and high levels are found in seronegative arthriti...
Autores principales: | Geven, Edwin J. W., van den Bosch, Martijn H. J., Di Ceglie, Irene, Ascone, Giuliana, Abdollahi-Roodsaz, Shahla, Sloetjes, Annet W., Hermann, Sven, Schäfers, Michael, van de Loo, Fons A. J., van der Kraan, Peter M., Koenders, Marije I., Foell, Dirk, Roth, Johannes, Vogl, Thomas, van Lent, Peter L. E. M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078998/ https://www.ncbi.nlm.nih.gov/pubmed/27776554 http://dx.doi.org/10.1186/s13075-016-1121-z |
Ejemplares similares
-
S100A8/A9 increases the mobilization of pro-inflammatory Ly6C(high) monocytes to the synovium during experimental osteoarthritis
por: Cremers, Niels A. J., et al.
Publicado: (2017) -
Fcγ receptor-mediated influx of S100A8/A9-producing neutrophils as inducer of bone erosion during antigen-induced arthritis
por: Di Ceglie, Irene, et al.
Publicado: (2018) -
Nox2 Deficiency Reduces Cartilage Damage and Ectopic Bone Formation in an Experimental Model for Osteoarthritis
por: Kruisbergen, Nik N. L., et al.
Publicado: (2021) -
The alarmins S100A8 and S100A9 mediate acute pain in experimental synovitis
por: Blom, Arjen B., et al.
Publicado: (2020) -
IL-1β-Mediated Activation of Adipose-Derived Mesenchymal Stromal Cells Results in PMN Reallocation and Enhanced Phagocytosis: A Possible Mechanism for the Reduction of Osteoarthritis Pathology
por: van Dalen, Stephanie C. M., et al.
Publicado: (2019)