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Efficacy of artemether-lumefantrine in relation to drug exposure in children with and without severe acute malnutrition: an open comparative intervention study in Mali and Niger

BACKGROUND: Severe acute malnutrition (SAM) affects almost all organs and has been associated with reduced intestinal absorption of medicines. However, very limited information is available on the pharmacokinetic properties of antimalarial drugs in this vulnerable population. We assessed artemether-...

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Detalles Bibliográficos
Autores principales: Denoeud-Ndam, Lise, Dicko, Alassane, Baudin, Elisabeth, Guindo, Ousmane, Grandesso, Francesco, Diawara, Halimatou, Sissoko, Sibiri, Sanogo, Koualy, Traoré, Seydou, Keita, Sekouba, Barry, Amadou, de Smet, Martin, Lasry, Estrella, Smit, Michiel, Wiesner, Lubbe, Barnes, Karen I., Djimde, Abdoulaye A., Guerin, Philippe J., Grais, Rebecca F., Doumbo, Ogobara K., Etard, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079061/
https://www.ncbi.nlm.nih.gov/pubmed/27776521
http://dx.doi.org/10.1186/s12916-016-0716-1