Cargando…

Efficacy of artemether-lumefantrine in relation to drug exposure in children with and without severe acute malnutrition: an open comparative intervention study in Mali and Niger

BACKGROUND: Severe acute malnutrition (SAM) affects almost all organs and has been associated with reduced intestinal absorption of medicines. However, very limited information is available on the pharmacokinetic properties of antimalarial drugs in this vulnerable population. We assessed artemether-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Denoeud-Ndam, Lise, Dicko, Alassane, Baudin, Elisabeth, Guindo, Ousmane, Grandesso, Francesco, Diawara, Halimatou, Sissoko, Sibiri, Sanogo, Koualy, Traoré, Seydou, Keita, Sekouba, Barry, Amadou, de Smet, Martin, Lasry, Estrella, Smit, Michiel, Wiesner, Lubbe, Barnes, Karen I., Djimde, Abdoulaye A., Guerin, Philippe J., Grais, Rebecca F., Doumbo, Ogobara K., Etard, Jean-François
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079061/ https://www.ncbi.nlm.nih.gov/pubmed/27776521 http://dx.doi.org/10.1186/s12916-016-0716-1

Ejemplares similares

Severe Acute Malnutrition Results in Lower Lumefantrine Exposure in Children Treated With Artemether‐Lumefantrine for Uncomplicated Malaria
por: Chotsiri, Palang, et al.
Publicado: (2019)

A multi-center, open-label trial to compare the efficacy and pharmacokinetics of Artemether-Lumefantrine in children with severe acute malnutrition versus children without severe acute malnutrition: study protocol for the MAL-NUT study
por: Denoeud-Ndam, Lise, et al.
Publicado: (2015)

Monitoring of the Sensitivity In Vivo of Plasmodium falciparum to Artemether-Lumefantrine in Mali
por: Diarra, Modibo, et al.
Publicado: (2021)

Efficacy of artesunate–amodiaquine, dihydroartemisinin–piperaquine and artemether–lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Maradi, Niger
por: Grandesso, Francesco, et al.
Publicado: (2018)

Efficacy and safety of a fixed dose artesunate-sulphamethoxypyrazine-pyrimethamine compared to artemether-lumefantrine for the treatment of uncomplicated falciparum malaria across Africa: a randomized multi-centre trial
por: Sagara, Issaka, et al.
Publicado: (2009)

A randomized trial of dihydroartemisinin–piperaquine versus artemether–lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Mali
por: Dama, Souleymane, et al.
Publicado: (2018)

Safety of Single-Dose Primaquine in G6PD-Deficient and G6PD-Normal Males in Mali Without Malaria: An Open-Label, Phase 1, Dose-Adjustment Trial
por: Chen, Ingrid, et al.
Publicado: (2018)

Reduced ex vivo susceptibility of Plasmodium falciparum after oral artemether–lumefantrine treatment in Mali
por: Dama, Souleymane, et al.
Publicado: (2017)

Anaemia in a phase 2 study of a blood stage falciparum malaria vaccine
por: Ellis, Ruth D, et al.
Publicado: (2011)

Impact of intermittent preventive treatment with sulphadoxine-pyrimethamine targeting the transmission season on the incidence of clinical malaria in children in Mali
por: Dicko, Alassane, et al.
Publicado: (2008)

Selection of pfcrt K76 and pfmdr1 N86 Coding Alleles after Uncomplicated Malaria Treatment by Artemether-Lumefantrine in Mali
por: Maiga, Hamma, et al.
Publicado: (2021)

Two-Year Scale-Up of Seasonal Malaria Chemoprevention Reduced Malaria Morbidity among Children in the Health District of Koutiala, Mali
por: Maiga, Hamma, et al.
Publicado: (2020)

Persistence of mRNA indicative of Plasmodium falciparum ring-stage parasites 42 days after artemisinin and non-artemisinin combination therapy in naturally infected Malians
por: Mahamar, Almahamoudou, et al.
Publicado: (2021)

Intermittent Preventive Treatment of Malaria Provides Substantial Protection against Malaria in Children Already Protected by an Insecticide-Treated Bednet in Mali: A Randomised, Double-Blind, Placebo-Controlled Trial
por: Dicko, Alassane, et al.
Publicado: (2011)

Safety of epoietin beta-quinine drug combination in children with cerebral malaria in Mali
por: Picot, Stéphane, et al.
Publicado: (2009)

Pyronaridine–artesunate or dihydroartemisinin–piperaquine combined with single low-dose primaquine to prevent Plasmodium falciparum malaria transmission in Ouélessébougou, Mali: a four-arm, single-blind, phase 2/3, randomised trial
por: Stone, William, et al.
Publicado: (2022)

Mechanistic Modeling of Primaquine Pharmacokinetics, Gametocytocidal Activity, and Mosquito Infectivity
por: Chotsiri, Palang, et al.
Publicado: (2022)

Repeated Artemisinin-Based Combination Therapies in a Malaria Hyperendemic Area of Mali: Efficacy, Safety, and Public Health Impact
por: Sagara, Issaka, et al.
Publicado: (2012)

Delivery strategies for malaria vaccination in areas with seasonal malaria transmission
por: Grant, Jane, et al.
Publicado: (2023)

Efficacy and safety of primaquine and methylene blue for prevention of Plasmodium falciparum transmission in Mali: a phase 2, single-blind, randomised controlled trial
por: Dicko, Alassane, et al.
Publicado: (2018)

Plasmodium falciparum clearance with artemisinin-based combination therapy (ACT) in patients with glucose-6-phosphate dehydrogenase deficiency in Mali
por: Kone, Abdoulaye K, et al.
Publicado: (2010)

Cost of introducing and delivering malaria vaccine (RTS, S/AS01(E)) in areas of seasonal malaria transmission, Mali and Burkina Faso
por: Diawara, Halimatou, et al.
Publicado: (2023)

Seasonal Malaria Chemoprevention with Sulphadoxine-Pyrimethamine and Amodiaquine Selects Pfdhfr-dhps Quintuple Mutant Genotype in Mali
por: Maiga, Hamma, et al.
Publicado: (2016)

Space-time clustering of childhood malaria at the household level: a dynamic cohort in a Mali village
por: Gaudart, Jean, et al.
Publicado: (2006)

Protection of Malian children from clinical malaria is associated with recognition of multiple antigens
por: Daou, Modibo, et al.
Publicado: (2015)

Measuring the impact of seasonal malaria chemoprevention as part of routine malaria control in Kita, Mali
por: Diawara, Fatou, et al.
Publicado: (2017)

“Spatial heterogeneity of environmental risk in randomized prevention trials: consequences and modeling”
por: Guindo, Abdoulaye, et al.
Publicado: (2019)

The implementation of malaria intermittent preventive trialtreatment with sulphadoxine-pyrimethamine in infants reduced all-cause mortality in the district of Kolokani, Mali: results from a cluster randomized control
por: Dicko, Alassane, et al.
Publicado: (2012)

Development of a pediatric formulation for treatment of P. falciparum malaria: Coartem(®) (artemether-lumefantrine) Dispersible
por: Bassat, Quique, et al.
Publicado: (2014)

Increase in EPI vaccines coverage after implementation of intermittent preventive treatment of malaria in infant with Sulfadoxine -pyrimethamine in the district of Kolokani, Mali: Results from a cluster randomized control trial
por: Dicko, Alassane, et al.
Publicado: (2011)

Persistence of Plasmodium falciparum HRP-2 antigenaemia after artemisinin combination therapy is not associated with gametocytes
por: Oulton, Tate, et al.
Publicado: (2022)

Shifts in the clinical epidemiology of severe malaria after scaling up control strategies in Mali
por: Coulibaly, Drissa, et al.
Publicado: (2022)

Molecular markers of resistance to sulphadoxine-pyrimethamine one year after implementation of intermittent preventive treatment of malaria in infants in Mali
por: Dicko, Alassane, et al.
Publicado: (2010)

Dynamics of Polymorphism in a Malaria Vaccine Antigen at a Vaccine-Testing Site in Mali
por: Takala, Shannon L, et al.
Publicado: (2007)

Efficacy of chloroquine, amodiaquine and sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria: revisiting molecular markers in an area of emerging AQ and SP resistance in Mali
por: Tekete, Mamadou, et al.
Publicado: (2009)

Development of a dissolution method for lumefantrine and artemether in immediate release fixed dose artemether/lumefantrine tablets
por: Belew, Sileshi, et al.
Publicado: (2020)

Recent malaria does not substantially impact COVID-19 antibody response or rates of symptomatic illness in communities with high malaria and COVID-19 transmission in Mali, West Africa
por: Woodford, John, et al.
Publicado: (2022)

The clinical efficacy of artemether/lumefantrine (Coartem(®))
por: Makanga, Michael, et al.
Publicado: (2009)

Transmission-blocking Effects of Primaquine and Methylene Blue Suggest Plasmodium falciparum Gametocyte Sterilization Rather Than Effects on Sex Ratio
por: Bradley, John, et al.
Publicado: (2019)

Phase 1 Study of a Combination AMA1 Blood Stage Malaria Vaccine in Malian Children
por: Dicko, Alassane, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_tlm4cas9t6jdmpjbjcj8qkuejd