Judicious Toggling of mTOR Activity to Combat Insulin Resistance and Cancer: Current Evidence and Perspectives

The mechanistic target of rapamycin (mTOR), via its two distinct multiprotein complexes, mTORC1, and mTORC2, plays a central role in the regulation of cellular growth, metabolism, and migration. A dysregulation of the mTOR pathway has in turn been implicated in several pathological conditions includ...

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Detalles Bibliográficos
Autores principales: Ong, Pei Shi, Wang, Louis Z., Dai, Xiaoyun, Tseng, Sheng Hsuan, Loo, Shang Jun, Sethi, Gautam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079084/
https://www.ncbi.nlm.nih.gov/pubmed/27826244
http://dx.doi.org/10.3389/fphar.2016.00395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079084/
https://www.ncbi.nlm.nih.gov/pubmed/27826244
http://dx.doi.org/10.3389/fphar.2016.00395

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