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Slow Conduction in the Border Zones of Patchy Fibrosis Stabilizes the Drivers for Atrial Fibrillation: Insights from Multi-Scale Human Atrial Modeling

Introduction: The genesis of atrial fibrillation (AF) and success of AF ablation therapy have been strongly linked with atrial fibrosis. Increasing evidence suggests that patient-specific distributions of fibrosis may determine the locations of electrical drivers (rotors) sustaining AF, but the unde...

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Detalles Bibliográficos
Autores principales: Morgan, Ross, Colman, Michael A., Chubb, Henry, Seemann, Gunnar, Aslanidi, Oleg V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079097/
https://www.ncbi.nlm.nih.gov/pubmed/27826248
http://dx.doi.org/10.3389/fphys.2016.00474