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Apoptosis in response to microbial infection induces autoreactive T(H)17 cells

Microbial infections often precede the onset of autoimmunity. How infections trigger autoimmunity remains poorly understood. We investigated the possibility that infection might create conditions that allow the stimulatory presentation of self peptides themselves and that this might suffice to elici...

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Detalles Bibliográficos
Autores principales: Campisi, Laura, Barbet, Gaetan, Ding, Yi, Esplugues, Enric, Flavell, Richard A., Blander, J. Magarian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079524/
https://www.ncbi.nlm.nih.gov/pubmed/27455420
http://dx.doi.org/10.1038/ni.3512